Vitamin K (Quinones) helps with gamma-carboxylation of coagulation factors II, VII, IX, and X.
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Vitamin K (phytomenadione)
———————————————
Characteristics

Synonyms
Vitamin K1 (phytomenadione, phytonadione, or phylloquinone)
Vitamin K2 (menaquinone)
Active form: vitamin K hydroquinone; activation occurs via enzyme epoxide reductase

Sources
————-
Leafy green vegetables (vitamin K1)
Eggs, dairy, and meat (vitamin K2)
Synthesized in small amounts by intestinal flora

Storage: liver

Functions
—————–
Cofactor for γ-carboxylation of glutamic acid residues in vitamin-K-dependent proteins that are involved in
Coagulation: factors II (prothrombin), VII, IX, and X, proteins C and S
Bone formation: osteocalcin (bone Gla protein), matrix Gla protein

#vitamink #vitaminkvideo #vitaminkusmle #vitaminksources #vitaminkdeficiency

Vitamin K Deficiency | Dietary Sources, Causes, Symptoms, Diagnosis, Treatment

*Re-uploaded to correct error with initial upload*

Vitamin K Deficiency involves many causes including decreased dietary intake, decreased absorption of Vitamin K, and certain medications. Vitamin K Deficiency leads to issues involving coagulation factors and bone mineralization. In this lesson, we discuss the signs and symptoms of Vitamin K Deficiency along with methods to diagnosis and ways to treat it.

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REFERENCES:
Vitamin K Deficiency, StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK536983/

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