Ted Striker tells Dr. Oz how the “If/Then” Technique helps him crush his food cravings.
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Insulin Overview

Insulin is a fat storing hormone because it increases the major fat storing enzyme in the body called lipoprotein lipase (LPL)

It also decreases hormone sensitive lipase (HSL), the major fat burning enzyme, and slows fat oxidation by suppression of CPT-1 (the rate limiting step in fat burning)

So if decrease insulin, fat storage becomes slowed while fat release and burning is sped up

Other Fat Storing Hormones

Aside from insulin, there are (at least) 2 other fat storing hormones

One of them is called acylation stimulating protein (ASP) – where insulin is induced by carbs, ASP is induced by fat and both ASP and insulin stimulate the secretion of each other

So fat does stimulate insulin & insulin stimulates a fat storing helper ASP

Another storing hormone is a gut produced signaling molecule called glucose-dependent insulinotropic peptide (GIP)

GIP is induced by both carbs & fat – GIP has its own fat storing action on LPL and causes more insulin to be released

Glucose-dependent insulinotropic peptide (GIP)

Glucose-dependent insulinotropic peptide is a hormone released from the small intestine that enhances the release of insulin following the intake of food.

Glucose-dependent insulinotropic peptide is made and secreted mainly from the upper section of the small intestine from a specific type of cell known as the K cell

Its main action occurs in the pancreas where it targets beta cells, which produce insulin. Glucose-dependent insulinotropic peptide stimulates the release of insulin from the beta cells in the pancreas in order to maintain low blood sugar levels after eating.

The main trigger for glucose-dependent insulinotropic peptide release is food, in particular fatty foods or those foods that are rich in sugar.

Once released into the bloodstream, levels of glucose-dependent insulinotropic peptide do not remain high for very long. It is broken down quite quickly (after about seven minutes) and therefore does not remain in the circulating blood for long.

Acylation Stimulating Protein (ASP)

ASP is produced through a process involving three proteins: C3, factor B and adipsin, which are secreted by adipocytes – it’s an adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes

ASP has a primary role in the regulation of lipid metabolism in adipocytes, where it stimulates glucose uptake, increases the activity of diacylglycerol acyltransferase, and inhibits hormone-sensitive lipase activity

In cellular studies, ASP increases fat storage through increased triglyceride synthesis and decreased intracellular lipolysis

Fats & Carbs

This means both carbs and fat cause fat gain, and when they are combined together they can result in even more

Eat carbs and you release insulin, and you also release GIP – GIP also causes the release of insulin itself

ASP is stimulated directly by fat and is stimulated indirectly by carbs because insulin stimulates ASP as well, and then ASP stimulates insulin

References

1) Ahrén B , et al. (n.d.). Acylation stimulating protein stimulates insulin secretion. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/12917708

2) Metabolic response of Acylation Stimulating Protein to an oral fat load. (n.d.). Retrieved from http://www.jlr.org/content/30/11/1727

3) The worst food combination for weight loss. (n.d.). Retrieved from https://www.metaboliceffect.com/worst-food-combination-for-weight-loss/

4) You and Your Hormones. (n.d.). Retrieved from http://www.yourhormones.info/hormones/glucose-dependent-insulinotropic-peptide/

5) McIntosh CH , et al. (n.d.). Glucose-dependent insulinotropic polypeptide (Gastric Inhibitory Polypeptide; GIP). – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/19251046

6) Critical review of acylation-stimulating protein physiology in humans and rodents. (n.d.). Retrieved from https://www.sciencedirect.com/science/article/pii/S0005273602006867

7) Acylation-Stimulating Protein (ASP). (n.d.). Retrieved from https://www.biovendor.com/acylation-stimulating-protein

8) The effects of acylation stimulating protein supplementation VS antibody neutralization on energy expenditure in wildtype mice. (n.d.). Retrieved from https://bmcphysiol.biomedcentral.com/articles/10.1186/1472-6793-10-4

9) https://www.nature.com/articles/0802369#ref14

10) Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward. (n.d.). Retrieved from https://www.sciencedirect.com/science/article/pii/S1550413118303255
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Which vitamins are actually good for you? There’s a fine line between helping your health and hurting it. Here’s a guide on the “ABCs” of vitamin intake that’ll help you improve the condition of your skin, hair and overall health.

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How to Get the Most out of Vitamin Supplements- Thomas DeLauer:
When should you take your vitamins? To learn more about how I can help you, head to http://www.ThomasDeLauer.com
Many factors play a role on how available vitamins and supplements are when you take them. Fat-Soluble Vitamins: Vitamins A, D, E and K-
These are stored in the liver and fat stores in your body, so you do not need to consume these every day. They are easy to get from food as they are not easily broken down by heat when cooking. These are the most important vitamins to eat with food, as the name implies, they are only absorbed and used by the body in the presence of fat. These vitamins dissolve in fat and are then delivered to the bloodstream for use in the body. Not much fat is needed, but if taking a supplement, or even eating fruits and veggies, but sure to have some fat added. If you make a healthy smoothie, add some almond butter or you favorite oil, such as macadamia nut oil. When eating salads, do not use fat-free salad dressings! Olive oil and lemon juice are great options. Be careful if you supplement these vitamins and be sure to check with your doctor if you feel you may need to do so. These vitamins are only needed in small quantities and can build up to a dangerous level if too many are taken. Vitamin D is the main fat-soluble vitamin in the US where deficiencies are common. This is due to inadequate exposure to sunlight. Fortified foods and supplements can help. Try to obtain 5-15 minutes of direct sunlight twice per week to avoid a deficiency, and if this is not possible then talk to your doctor about supplementation.
Water-Soluble Vitamins: Vitamin C and B-complex vitamins are water soluble vitamins that you need to be sure to include in your diet daily. Unlike fat-soluble vitamins, these vitamins are not stored in your adipose tissue or liver and are in essence washed from your body daily. Food storage and preparation are important when making sure to get sufficient quantities of these vitamins. Deficiencies are uncommon, however vegans do not have a natural source of vitamin B12 and usually need to supplement. While deficiencies are not common, it is still important to consume daily for bodily functioning. As these vitamins dissolve in water, you do not need to take these with foods, although you can if you want to.
Minerals: Calcium and Magnesium (2,4) – These are best taken with food and good to take at night. Calcium is linked to improved sleep due to its muscle relaxing abilities and magnesium has calming effects on the nervous and musculoskeletal systems.
Zinc (2,4) – Take with or after meals to avoid stomach upset. Do not take with dairy as calcium hampers absorption. Also avoid taking with iron as large quantities of iron can also hurt your body’s ability to absorb zinc. Avoid taking excess zinc, which can lead to anemia through suppression of copper absorption.
Iron (4) – Best to take on an empty stomach. Avoid taking with zinc, calcium and vitamin E as these can decrease absorption. If you have a sensitive stomach you may not do well when taking iron on an empty stomach. If so, take with a light meal.
Probiotics (4) – Best to take 30 minutes before a meal as this is when digestive enzymes, bile salts and stomach acid are at low levels. These levels peak after a meal, so this is the worst time to take a probiotic.
Fiber (2) – Be sure to separate taking fiber from other nutritional supplements as fiber can hamper mineral absorption.
Fish Oil (4) – Fish Oil is best to take with food and with your multivitamin, or other fat-soluble vitamins, if you take them. The fat in the food that you eat can help to aid in digestion and absorption. As fats take a long time for your body to digest, it is best not to take fish oil pills or eat a fatty meal pre-workout. This can cause digestive upset.
Multivitamins: As these contain both water- and fat-soluble vitamins, take with plenty of water and some food with fat in it, but try not to take with dairy as this can reduce your absorption of zinc.
References:
1. Fat-soluble vitamins

Fat-Soluble Vitamins: A, D, E, and K – 9.315

2. Water-soluble vitamins
http://extension.colostate.edu/topic-areas/nutrition-food-safety-health/water-soluble-vitamins-b-complex-and-vitamin-c-9-312/
3. Get the most from your vitamin supplements
http://www.foxnews.com/health/2014/04/08/get-most-from-your-vitamin-supplements.html
4. A guide to timing supplement intake
https://labdoor.com/article/a-guide-to-timing-supplement-intake/

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Sometimes medications that were developed to treat one condition can end up being useful for seemingly unrelated ailments.

Hosted by: Michael Aranda

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Sources:
Dextromethorphan
https://www.ncbi.nlm.nih.gov/pubmed/19137121
https://www.ncbi.nlm.nih.gov/pubmed/21476614
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849173/

Memantine
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123289
https://www.nimh.nih.gov/health/topics/obsessive-compulsive-disorder-ocd/index.shtml
https://www.ncbi.nlm.nih.gov/pubmed/23525525
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540409/
https://www.ncbi.nlm.nih.gov/pubmed/24406251

Naltrexone
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851054/ https://www.samhsa.gov/medication-assisted-treatment/treatment/naltrexone
https://www.samhsa.gov/sites/default/files/programs_campaigns/medication_assisted/efficacy-naltrexone-treatment-alcohol-dependence.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666924/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164585/
https://www.ncbi.nlm.nih.gov/pubmed/28877518
https://academic.oup.com/alcalc/article/48/4/402/533312

Sildenafil
https://www.mayoclinic.org/diseases-conditions/pulmonary-hypertension/symptoms-causes/syc-20350697
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994020/

Phosphodiesterase 5 inhibitors

Spironolactone
http://www.internationaljournalofcardiology.com/article/S0167-5273(15)01190-0/fulltext
https://www.ncbi.nlm.nih.gov/pubmed/10760075
http://www.academia.edu/13992257/Vanders_Human_Physiology_-_The_Mechanisms_of_Body_Function
https://academic.oup.com/endo/article-abstract/97/1/52/2619110?redirectedFrom=fulltext
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315877/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994020/

Propranolol
https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/beta-blockers/art-20044522
http://www.heart.org/HEARTORG/Conditions/HeartAttack/DiagnosingaHeartAttack/Angina-Pectoris-Stable-Angina_UCM_437515_Article.jsp#.Wn-zBJMbO-o
https://www.ncbi.nlm.nih.gov/pubmed/26487439
https://www.sciencedirect.com/science/article/pii/027858469290004X?via%3Dihub

Minoxidil
http://onlinelibrary.wiley.com/doi/10.1111/j.1524-6175.2004.03585.x/full
https://www.ncbi.nlm.nih.gov/pubmed/14996087
https://www.hshairclinic.co.uk/hair-loss/all-about-hair/hair-cycle/
https://www.karger.com/Article/Pdf/248894

Bimatoprost
https://www.aao.org/eye-health/diseases/what-is-glaucoma
https://www.latisse.com/AboutLatisse.aspx
https://www.ncbi.nlm.nih.gov/pubmed/20384750
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021275s022lbl.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769924/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861943/
———-
Images:
http://www.thinkstockphotos.com/image/stock-photo-bottles-of-pills-in-cabinet-close-up/103583051
https://en.wikipedia.org/wiki/File:Dextrometorfano.jpg
http://www.thinkstockphotos.com/image/stock-illustration-body-organs/510154886
http://www.thinkstockphotos.com/image/stock-illustration-brain-polygon/666908262
https://commons.wikimedia.org/wiki/File:Pachinko_parlor_dsc04790.jpg
http://www.thinkstockphotos.com/image/stock-photo-opioid-epidemic-and-drug-abuse-concept/829000374
https://commons.wikimedia.org/wiki/File:Pulmonary_hypertensive_arteriopathy_(4348170715).jpg
http://www.thinkstockphotos.com/image/stock-illustration-acne-vulgaris-or-pimple-healthy-hair/875814728
https://commons.wikimedia.org/wiki/File:Propranolol_tablets.png
http://www.thinkstockphotos.com/image/stock-illustration-man-scratching-his-head-and-hair/840062408
http://www.thinkstockphotos.com/image/stock-photo-closeup-young-man-serious-hair-loss-problem/596370890

NCLEX pharmacology review practice question on beta blocker medications.

On the NCLEX exam, it is inevitable you will receive pharmacology type questions. This NCLEX-style question will test your ability on how to analyze a scenario for a patient taking the beta blocker medication Propranolol.

This video is part of a weekly NCLEX review series where I will be going over NCLEX-style questions with you. I will be helping you analyze and breakdown each question, and walk you through how to select the correct option.

NCLEX questions require critical thinking and you must know how to use your nursing knowledge to gather the facts and analyze what the question is asking.

For this specific NCLEX practice question, you must know the basics about the drug Propranolol and the correct education to provide a patient.

NCLEX Practice Pharmacology Question:

A patient, who has a health history of uncontrolled hypertension, coronary artery disease, and diabetes mellitus, is prescribed to take Propranolol. You have provided the patient with education about this new medication. Which statement by the patient indicates your teaching was effective?

A. “I will take this medication every morning with grapefruit juice.”
B. “If I miss a dose, it is important that I double the next dose to prevent potential side effects.”
C. “It is important that I monitor my blood glucose levels very closely while taking this medication.”
D. “I will immediately stop taking this medication if I experience cold hands or feet.”

Watch the video for the correct answer and rationale.

Free NCLEX practice quizzes: http://www.registerednursern.com/nursing-student-quizzes-tests/

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Is healthcare a right or a luxury? The answer each individual gives to that question depends largely on their previous experiences with medical care, and on their geographical background and personal philosophy. It is not as simple as it sounds. But the world is getting smaller, and it is imperative that we develop a shared understanding of what kind of healthcare system works best for society in general, and how to fund this effectively. In this talk, Tarik Sammour challenges the audience to think about these questions and engages them in a passionate debate, while putting his own personal spin on things as all good speakers do! Tarik Sammour is a surgeon at the Royal Adelaide Hospital and an Associate Professor at the University of Adelaide, specialising in advanced bowel cancer surgery, patient outcome centred research and robotics. Throughout his training, Tarik has been privileged to work in a wide variety of healthcare systems, from the smallest general hospital in rural New Zealand to one of the largest medical centres in the United States, giving him a unique first-hand insight into what works well for patients and what doesn’t. One of the reasons he eventually chose to settle in Adelaide was because he saw the city’s potential as a leader in healthcare delivery and innovation. With an ageing population and spiralling healthcare costs, he has some ideas to solve problems that are relevant to us all. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
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You probably know a couple who both work full time to support their children, but even with their dual incomes, they’re finding it more and more difficult to afford health insurance. Everyday incidents like sports injuries, asthma, and blood pressure, combined with their anxiety over rising premiums, are turning their American dream into sleepless nights. Why can’t people catch a break? It wasn’t always this way!

Check out the transcript of this episode aind out more about how we got here at FEE: https://fee.org/articles/health-care-is-a-mess-but-why/

And download FEE’s new Essential Guide to Health Care Reform: http://hubs.ly/H087jP20

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Written by Seamus Coughlin & Sean Malone
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In this video, pharmacist Linda Awdishu, PharmD MAS at UC San Diego Health (http://health.ucsd.edu/nephrology) discusses medications used to lower high blood pressure and high cholesterol, as well as medicines used to maintain your kidney health.

For more information about kidney disease treatment at UC San Diego Health, see http://health.ucsd.edu/nephrology.
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Official music video for “Medication [Remix]” by Damian “Jr. Gong” Marley ft. Stephen “Ragga” Marley, Wiz Khalifa & Ty Dolla $ ign. | Get the remix: https://dmar.ly/medicationrmx
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© 2018 Republic Records, a division of UMG Recordings, Inc.
_______________________________________

“MEDICATION REMIX” Lyrics:
Stephen “Ragga” Marley
CHORUS 1
Medication
Your medication makes me high
Just be patient
I’m like a patient trying to find
Levitation
Run your fingers down my spine
Elevation
Your medication makes me high Eh!

Ty Dolla $ ign
I fell in love with a sativa
Where you been
Nice to meet ya
It took so long for me to meet ya
Obsessed with ya features
You got all different flavors
You got that loud beat speakers
Your best friend Keisha
Know how to knock em out they sneakers
Like that Louis XIII but she nothing like my ex though
She remind me of gelato
Got me drinking out the bottle
She got me swerving on this shorty
Her name was indica
I tried to tell her I was sorry
She said that’s the end of us
But I can’t help but keep on rolling up
Medication keep me going up
Meditation come on breathe wit us
No ventilation keep the windows up

CHORUS 2
Damian “Jr. Gong” Marley
Such a short way up and such a long way down
Chalice it a bubble like we deh a Ray Town
Di way yuh sup’n nuff it haffi way by pound
Inna fields of Marijuana that is my playground
“I love you Mary-Jane”
You’re the prettiest of flowers girl mi can’t complain
When I’m with you I feel so high I rise above the rain
And yuh nuh do people damage like that bitch cocaine
No!
And leave them lonely feeling only pain
Cause
Your D.N.A. is of the highest strain
Your effect is so potent it’s so insane
Yuh so gummy and sticky like a plasticine
When mi grind out yuh body only stems remain
And to love you is so risky I might get detained
You always keep me flying on the highest plain
And anybody know will always proclaim…

CHORUS 3
Wiz Khalifa
You so fire
You so fire
The only thing I think of
When I need to unwind
See I been go crazy
Cause you been on mind
And something is wrong
But to me it’s not a crime
You can take me places
Just look at they faces
Plus you’re so good
That some don’t know what your taste is
Dealing with you complex
Nothing bout you basic
You the real deal
I could never fake it
I fell in love with the indica
Ever since I was young
I been into ya
Even when you’re almost done
Don’t wanna finish ya
It don’t matter where you at
Imma pick you up
Yeah, Imma pick you up
And we in for a good night
Imma wrap you up real tight
And if things get dark
I give you a light
Keep it with me
You been on my mind all night
Cause you my

CHORUS 4
_______________________________________

“MEDICATION REMIX” Music Video Credits:
Production Co: Scheme Engine
Director: James Larese
Executive Producer : Sheira Rees Davies
Producer: Christopher Salzgeber
DP: Sing Howe Yam
DP Additional Photography : Simon Thirlaway
Editor: Clark Eddy

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Michelle van Ryn, Ph.D., a researcher at Mayo Clinic, describes unconscious bias in health care and research underway to understand and address the issue.
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What are the best foods for health, weight loss, wellness and energy?
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Top 10 #SuperFoods – Psychetruth Nutrition, Whole Food, Corrina

What are the best foods for health, #weightloss, wellness and energy? Super Foods of course!! In this video Certified Holistic Health Coach Corrina Rachel counts down her top 10 favorites!

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How can you avoid travel delays upon arrival to, and departure from, the United States? That’s a question patients often ask their local pharmacist or the FDA. FDA Drug Info Rounds pharmacists outline key points pharmacists should counsel their patients on prior to travel.

[vpdrugs]

Check out the official music video for “Medication” by Damian “Jr. Gong” ft. Stephen Marley (Official Video)

Song Available Here: https://republic.lnk.to/MarleyMedicationYD

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Hi, guys! There’s a lot of misinformation out there on the topic of vitamins. Today, I’m focusing on two major vitamins that are causing a stir in this conversation: vitamin D and vitamin B12. Specifically, what’s true about vitamins D and B12 and what’s fake news?

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We all have friends who swear by their vitamin routine — their Vitamin C pills prevent them from getting colds, or their Vitamin D supplement really does boost their mood in the winter. But how much of this is the placebo effect? And how much of it actually works? The following vitamins are highly recommended for optimal health. Whether you decide to get these through nutritious foods or quick supplements is up to you…

Vitamin A | 0:24
Vitamin E | 1:20
Folate | 1:59
Vitamin C | 2:40
Vitamin B6 | 3:30
Vitamin B12 | 4:18
Vitamin D | 4:57
Calcium | 5:34
Magnesium | 6:22
Iron | 7:07
So, do we need vitamins? | 7:41

Read more here → http://www.thelist.com/28159/vitamins-actually-need-daily-basis/

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Get all these amazing superfoods in one scoop learn more at https://bit.ly/2PUCdAT
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SUMMARY:
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Superfoods are the most potent super nutrient rich foods on the planet. They have the ability to increase energy, detoxify the body, boost the immune system, lower inflammation in the body and completely nourish our bodies at the cellular level, which is where true healing takes place. Below are the super stars of the superfoods. Start to incorporate some of these super foods into your daily dietary lifestyle if you wish to experience optimal health. An easy way to accomplish this is by making a plant-based superfood smoothie. I have almost all my private clients incorporate superfoods into their dietary lifestyles. Today you can find these amazing super foods online or at almost any natural health food store. Below are my top ten favorite superfoods and why you should start including them into your diet right away.

1.Cacao (raw chocolate): Contains the world’s highest concentration of antioxidants in the world and is the #1 source of magnesium, iron, manganese and chromium. It has been known to improve cardiovascular health, builds strong bones and even create a good mood. In many cultures, cacao is considered a sacred food and with good reason.

2. Goji berries: Are the most nutritionally rich berry on the planet, they are 4 times more potent than blueberries. This berry is not only full of vitamins and trace minerals, but it is a complete protein source containing all 9 essential amino acids. This is why it has been used in traditional Chinese medicine for over 5,000 years.

3. Goji berries contain zinc, iron copper, calcium, germanium, selenium, phosphorus and vitamins B1, B2, B6 and E.

4. Camu camu berries: Contain the highest vitamin C source on the planet: 60 times more per serving than an orange. This berry is great for enhancing energy and the immune system. It contains an array of antioxidants and has been known to support cognitive function.

5. Spirulina: Is fresh water, single celled, spiral shaped, blue-green algae. It has the highest concentration of complete bioavailable protein (by weight) of any known food (65%). It provides a vast array of minerals, trace elements, phytonutrients and enzymes to support optimal health. It is a rich source of vitamin A, B1, B2, B6, E and K. It contains gamma-linoleic acid (GLA), which is an anti-inflammatory and nervous system essential.

6.Chlorella: Is a fresh water, single-celled, circle-shaped, green algae. It boosts the highest source of chlorophyll per gram than any other plant. It also is a complete protein (60%) by weight. It is also full of immune system and energy-boosting vitamins and minerals. It contains chlorella growth factor (CGF) which can increase tissue repair, supports probiotic growth and help fight free radicals (cancer causing cells). It is a rich source of vitamin A, B1, B2, B6, E and K.

7. Bee Products: Bee pollen is one of the most complete foods found in nature. It contains nearly all the B vitamins and 21 essential amino acids, making it a complete protein. Honey in its raw state is a rich source of minerals, antioxidants, probiotics and enzymes.

8. Maca: This sacred root has been cultivated in the high Peruvian Andes for thousands of years. It’s known for its adaptogenic effects of increasing energy, libido, strength and endurance. Look for maca that has been gelatinized. This process makes is more concentrated and easier to digest and absorb than raw maca powder.

9. Medicinal Mushrooms (Reishi, Chaga, Cordyseps, Maitake, Shitake): Have been used to help heal cancer and a variety of other diseases. They have super immune enhancing components.

10. Wheatgrass Juice: Having the nutritional value of 2 ½ lbs of leafy green vegetables per oz., freshly juiced wheat grass is 70% chlorophyll, which is an amazing blood detoxifier/cleanser. It is so nutrient dense (full of bioavailable vitamins, minerals, antioxidants and amino acids), that you could survive on wheat grass alone for quite some time.

10.Sunflower and Pea Sprouts: Sprouts contain 10-30 times the nutrient concentration of adult size vegetables. This is because when a seed is germinated it releases essential enzymes, vitamins, minerals and amino acids until it can draw these life giving components from the soil to grow. Sunflower and pea sprouts are also complete protein sources containing all 9 essential amino acids.

*For a free smoothie guide on how to make delicious smoothies using some of these amazing superfoods click the link in the video!
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